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T*
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[(weekly)-344(cycling)-344.4(duration)-344.3(was)-345(not)-343.3(associated)-343.8(with)-345.4(ED)-338.3(or)-342(in-)]TJ
T*
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T*
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T*
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T*
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[(study)-339.5(is)-347.7(one)-338.5(of)-347.8(many)-340.9(similarly)-346.7(designed)-345.1(works)-346(on)-342(exercise)]TJ
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[(and)-309.7(health)-314.5(that)-316.9(use)-315.3(large)-313.2(cross-sectional)-320.4(analysis)-316.3(to)-307.6(provide)]TJ
T*
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[(ents)-454.8(between)-455.7(exercise)-462.6(and)-453.7(health)-458.4(outcomes.)]TJ
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(35)Tj
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[(gradients)-294.5(between)-300.2(risk)-298(factor)-297(exposure)-293.1(and)-298.2(health)-297.2(outcomes)]TJ
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T*
[(health)-734.9(of)-733.7(cyclistsprovides)-737.4(important)-738.4(population)-732.5(data)]TJ
T*
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T*
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T*
[(cycl)-15.8(i)10.5(n).4(g)-310.6(e)-.8(ve)-15.8(n)9.6(t).3(s.)]TJ
7.3823 0 0 6.5614 368.6172 477.4676 Tm
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[(19)7.7(21)]TJ
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T*
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T*
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(22)Tj
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[(a)15(n)-375.5(ov)20.8(e)15(r)0(a)19.7(l)0(l)-365.3(p)16.2(re)19.7(va)25.4(le)19.6(nc)25.4(e)-376.6(o)0(f)-365(5)0(2)26.6(%)-376.5(ED)]TJ
-10.5633 -1.1116 TD
[(wa)18.8(s)-438.6(r)0(e)19.7(p)0(o)26.6(r)0(t)20.7(e)0(d)25.4(.)-446.9(In)-434.1(t)16.1(h)0(e)-435.3(U)0(.)23.4(S)0(.)-430.6(N)0(a)18.8(t)16.1(io)20.7(na)25.4(l)-444.7(H)0(e)18.8(a)15(lt)20.6(h)-444.6(a)15(nd)-434.2(So)21(c)15(i)0(a)19.6(l)-444.7(L)15(i)0(f)20.7(e)]TJ
T*
[(Su)21(r)16.2(v)0(e)19.7(y)0(,)-396.2(t)16.1(he)-395(pr)20.9(ev)25.4(al)19.5(e)15(n)0(c)19.7(e)-405.4(of)-393.8(se)19.9(xu)26.6(al)-395.2(dy)20.8(sf)26.8(un)20.8(ct)25.3(io)20.7(n)-404.3(i)0(n)-394(m)0(a)18.4(l)16.1(es)-394.8(\(n)20.9(ot)]TJ
T*
[(sp)21(e)15(c)0(i)19.5()0(c)-371.8(E)15(D\))-371.7(wa)18.8(s)-381(3)0(1)26.6(%)0(.)]TJ
7.3823 0 0 6.5614 153.9779 576.1132 Tm
(27)Tj
9.843 0 0 9.843 165.033 571.7479 Tm
[(In)-370.8(a)-382.4(E)0(u)25.4(r)0(o)20.9(p)0(e)25.4(a)0(n)-372(s)0(t)20.9(u)0(d)26.6(y)0(,)-373.2(t)0(h)26.5(e)-382.4(Co)19.8(lo)26.5(gn)20.8(e)]TJ
-10.4654 -1.1174 TD
[(st)20.9(u)16.2(d)0(y)-186.5(o)0(f)-186.5(m)0(e)24.2(n)-196.9(ag)19.7(e)15(d)-196.9(30)20.8(8)26.6(0)-196.9(y)0(e)19.7(a)0(r)25.5(s)0(,)-188.6(t)0(h)26.5(e)-198.1(pr)20.9(ev)25.4(al)19.5(e)15(n)0(c)19.7(e)-198.1(of)-186.5(se)25.6(lf)20.7(-r)26.7(ep)19.7(or)26.6(te)19.6(d)]TJ
0 -1.1116 TD
[(ED)-205.9(wa)18.8(s)-214(1)0(9)20.8(.)13.9(2%)19.8(,)-216.5(w)15.3(it)20.6(h)-214.2(a)-221.1(st)20.9(e)15(e)0(p)-205(a)0(g)19.7(e)0(-)25.5(r)0(e)19.7(l)0(a)25.3(t)0(e)19.6(d)-214.2(in)20.7(cr)25.5(ea)18.5(se)-204.8(fr)20.9(o)16.2(m)-221.2(2.)24.3(3%)-204.9(to)]TJ
T*
[(53)20.8(.)13.9(4)0(%)25.5(.)]TJ
7.3823 0 0 6.5614 89.2346 543.2313 Tm
-.0162 Tc
(28)Tj
9.843 0 0 9.843 98.6456 538.866 Tm
0 Tc
[(Ho)20(we)24.6(ve)19.7(r)16.2(,)-222.3(th)20.7(e)-221.1(p)0(r)26.6(e)0(v)19.7(a)15(le)19.6(nc)25.4(e)-226.9(o)16.2(f)-219.9(E)0(D)-211.6(i)0(n)-209.7(t)0(h)20.7(i)16.1(s)-225.5(c)15(oh)20.8(or)26.6(t)-225.9(\()16.2(8.)24.3(4%)19.8(\))]TJ
-3.7208 -1.1174 TD
[(is)-301.6(lo)20.7(w)15.3(e)0(r)-302.8(t)0(h)20.7(a)0(n)-302.9(t)0(h)26.5(a)0(t)-303(i)0(n)-301.8(o)0(t)20.7(h)16.2(er)-302.8(st)20.9(ud)20.8(i)16.1(e)0(s)19.9(.)-314.4(S)16.3(e)0(v)19.7(e)0(r)25.5(a)0(l)-303(r)0(e)19.7(a)0(s)25.6(o)0(n)20.8(s)-311.9(mi)19.5(g)16.2(h)0(t)-301.8(a)0(c)18.5(-)]TJ
0 -1.1116 TD
[(co)19.7(u)16.2(n)0(t)-353.7(f)0(o)20.9(r)-363.9(t)16.1(h)0(i)20.7(s)0(:)-353.5(o)0(n)26.6(e)-365.1(re)19.7(as)25.6(on)-353.5(mi)19.5(g)16.2(h)0(t)-353.7(b)0(e)-354.7(d)0(i)26.5(f)0(f)20.9(e)0(r)25.5(e)0(n)19.7(c)0(e)24.3(s)-363.8(in)-353.7(th)20.7(e)-365.1(q)16.2(ue)19.7(s-)]TJ
T*
[(ti)20.6(o)16.2(n)0(n)20.8(a)0(i)25.3(r)0(e)19.7(s)-225.5(u)16.2(s)0(e)19.9(d)-225.7(t)16.1(o)-225.7(as)19.9(se)25.6(ss)-214.9(ED)24.5(;)-225.9(a)0(n)25.4(o)0(t)20.7(h)0(e)25.4(r)-225.7(co)19.7(u)16.2(l)0(d)-215.4(b)0(e)-210.7(t)0(h)20.7(a)0(t)-210.8(t)0(h)20.7(e)-221.1(cy)19.7(cl)25.3(is)20.9(ts)]TJ
0 -1.1174 TD
[(st)20.9(u)16.2(d)0(i)20.7(e)0(d)-354.7(h)16.2(ad)-354.7(re)19.7(la)25.3(ti)20.6(v)16.2(e)0(l)19.5(y)-364(lo)20.7(w)-364.8(r)16.2(at)19.5(es)-354.5(of)-353.5(r)16.2(i)0(s)20.9(k)-364(fa)19.7(c)15(t)0(o)20.7(r)0(s)-353.3(f)0(o)26.6(r)-369.7(E)15(D)-364.8(\(e)19.7(.)13.9(g)0(.)24.3(,)]TJ
0 -1.1116 TD
[(sm)19.8(o)16.2(k)0(i)20.7(n)0(g)-290.2(a)0(n)25.4(d)-306.4(hy)26.6(pe)19.7(rt)26.5(en)19.7(si)20.9(o)16.2(n)0(\))-295.9(c)15(om)19.6(p)16.2(a)0(r)19.7(e)0(d)-291.3(w)0(i)19.8(t)16.1(h)-306.4(t)0(h)26.5(e)-307.5(ge)25.4(ne)19.7(ra)25.5(l)-306.5(p)16.2(op)20.8(u-)]TJ
T*
[(la)19.5(t)16.1(i)0(o)20.7(n)0(.)-281(I)0(n)20.9(d)0(e)25.4(e)0(d)19.7(,)-291.4(re)19.7(su)21(l)16.1(t)0(s)-284.4(o)0(f)-284.4(M)0(M)19(A)15.3(S)-294.7(d)0(e)19.7(m)15(on)20.8(st)20.9(r)16.2(a)0(t)19.5(e)0(d)-285.6(l)16.1(ow)20(er)-285.6(ra)25.5(te)19.6(s)-294.6(o)0(f)]TJ
0 -1.1174 TD
[(ED)-159.8(am)18.5(o)16.2(n)0(g)-163.5(c)15(yc)19.7(l)16.1(i)0(s)20.9(t)0(s)-157.6(c)0(o)19.7(m)15(pa)19.7(re)25.5(d)-173.9(t)0(o)-157.8(n)0(o)20.8(n)16.2(cy)19.7(cl)25.3(is)20.9(ts)20.9(;)-168.3(t)0(h)20.7(i)16.1(s)-173.7(w)0(a)24.6(s)-173.7(at)19.5(t)16.1(r)0(i)20.7(b)0(u)26.6(t)0(e)19.6(d)]TJ
0 -1.1116 TD
[(to)-382.5(im)19.5(p)16.2(r)0(o)20.9(v)0(e)25.4(d)-398.5(c)15(a)0(r)19.7(d)0(i)26.5(o)0(v)20.8(a)15(sc)19.9(ul)20.7(a)15(r)-398.5(h)16.2(e)0(a)18.5(l)0(t)26.3(h)-398.5(a)15(m)0(o)19.6(n)16.2(g)-398.5(c)15(yc)19.7(li)26.3(st)20.9(s.)]TJ
7.3823 0 0 6.5614 263.1684 455.5274 Tm
-.0162 Tc
(26)Tj
9.843 0 0 9.843 274.3369 451.1621 Tm
0 Tc
[(Ne)24.6(ve)19.7(r-)]TJ
-21.5701 -1.1116 TD
[(th)20.7(e)15(l)0(e)19.6(s)0(s)27(,)-291.4(af)19.7(t)16.1(e)0(r)-279.8(c)0(r)19.7(o)0(s)21(s)16.4(-s)21.1(ec)24.3(ti)20.6(on)26.6(al)-280(an)19.7(al)25.3(ys)21(is)26.7(,)-291.4(t)0(h)20.7(e)15(re)-279.8(wa)18.8(s)-288.9(n)0(o)-278.7(b)0(i)20.7(o)16.2(lo)20.7(gi)26.5(ca)18.5(l)]TJ
T*
[(gr)20.9(a)15(d)0(i)20.7(e)0(n)25.4(t)-197.1(be)25.4(tw)19.8(e)15(e)0(n)-187.7(c)15(yc)19.7(li)26.3(ng)-186.5(a)15(n)0(d)-186.5(E)15(D.)-184(Fu)21(r)16.2(t)0(h)20.7(e)0(r)25.5(m)0(o)19.6(r)16.2(e,)-184.2(th)20.7(e)-192.3(p)0(r)20.9(e)15(va)19.7(le)25.3(nc)19.7(e)]TJ
0 -1.1174 TD
[(of)-249.8(ED)-251.9(wa)18.8(s)-260.1(l)0(o)20.7(w)0(e)24.6(r)-266(th)26.5(an)-251(th)20.7(at)-251.2(in)-250(st)20.9(ud)26.6(ie)19.6(s)-260.1(o)0(n)-249.9(t)0(h)20.7(e)-261.4(wi)19.8(de)25.4(r)-266(p)0(o)26.6(p)0(u)20.8(l)0(a)25.3(t)0(i)20.6(o)16.2(n.)]TJ
0 -1.1116 TD
[(Wi)24.2(th)-261.5(th)20.7(i)16.1(s)-271.6(in)-261.5(mi)25.2(nd)20.8(,)-268.4(t)0(h)20.7(i)0(s)-261.3(s)0(t)26.7(u)0(d)20.8(y)-271.8(e)15(m)0(p)19.6(h)0(a)25.4(s)0(i)20.9(z)0(e)24.3(s)-271.6(th)20.7(a)15(t)-271.9(cy)19.7(cl)25.3(in)20.7(g)-271.8(a)15(nd)-261.4(ED)]TJ
T*
[(ma)24.2(y)-479.1(n)0(o)20.8(t)-479.3(sh)26.8(ar)19.7(e)-480.3(a)-480.3(s)0(i)20.9(m)15(pl)20.7(e)-480.3(c)15(au)19.7(se)25.6(-a)19.7(nd)26.6(-e)19.7(ff)26.7(ec)18.5(t)-479.3(r)0(e)25.5(l)0(a)19.6(t)16.1(io)20.7(ns)21(h)16.2(i)0(p)20.7(.)-475.7(Th)19.6(e)]TJ
0 -1.1174 TD
[(pr)20.9(e)15(v)0(i)20.7(o)0(u)26.6(s)-179.5(st)20.9(ud)26.6(ie)19.6(s)-179.5(e)0(x)25.4(p)0(l)20.7(o)0(r)26.6(i)0(n)20.7(g)-179.6(E)15(D)-180.5(an)19.7(d)-179.6(c)15(yc)19.7(li)26.3(ng)-169.2(m)15(a)0(y)-170.4(o)0(v)20.8(e)15(re)19.7(m)15(p)0(h)20.8(a)0(s)25.6(i)0(z)19.6(e)]TJ
0 -1.1116 TD
[(it)20.6(s)-271.6(s)0(i)26.7(g)0(n)20.8(i)0()26.6(c)0(a)18.5(n)0(c)25.4(e)-273(am)18.5(o)16.2(n)0(g)-261.4(r)0(e)19.7(g)16.2(ul)20.7(a)15(r)-277.5(c)15(y)0(c)19.7(l)16.1(is)20.9(ts)-261.3(an)25.4(d)-271.8(d)0(o)-261.4(n)0(o)20.8(t)-271.9(a)15(c)0(c)18.5(o)0(u)26.6(n)0(t)-261.5(f)0(o)20.9(r)]TJ
T*
[(th)20.7(e)-267.2(c)0(a)24.3(r)0(d)20.9(i)0(o)26.5(v)0(a)19.7(s)0(c)25.6(u)0(l)20.7(a)0(r)-256.8(b)0(e)25.4(n)0(e)19.7()0(t)26.6(s)-271.6(th)26.5(at)-256.9(ca)18.5(n)-266(p)0(r)20.9(e)15(ve)19.7(nt)-255.8(ED)24.5(.)]TJ
1.0137 -1.1174 TD
-.0164 Tc
[(There)-191.4(w)4.7(as)-190.1(no)-190.3(dir)5.6(ect)-190.4(relat)5.4(i)-.3(on)5.5(ship)-190.3(between)-190.3(c)-1.4(y)5.5(c)-1.4(lin)5.5(g)-190.3(hour)5.6(s/week)]TJ
-1.0137 -1.1116 TD
-.0157 Tc
[(an)6.2(d)-247.2(r).5(isk)-247.2(o)6.2(f)-247.2(i).4(nf)6.3(erti)6.1(lit)6.1(y.)-249.5(C)5.2(o).5(mp)6.2(are)5.1(d)-247.2(to)-247.2(cy)6.2(cli)6.1(n).5(g)]TJ
/F6 1 Tf
16.9796 0 TD
0 Tc
(<)Tj
/F5 1 Tf
.7027 0 TD
-.0163 Tc
[(3)5.6(.)-2.4(7)5.6(5)-247.8(hou)5.6(rs/week)5.6(,)]TJ
-17.6823 -1.1116 TD
-.0165 Tc
[(cy)5.4(clin)5.4(g)-363.2(3)5.4(.7)5.4(55.7)5.4(5)-363.2(ho)5.4(urs/)5.3(w)-1.2(eek)-363.2(w)-1.2(as)-363(associat)5.3(ed)-363.2(with)-357.4(a)-364.3(r)5.5(edu)5.4(ced)]TJ
T*
-.0168 Tc
[(od)5.1(ds)-323(rati)5(o)-323.2(o)-.6(f)-323.1(0)-.6(.44)-323.2(\(95)5.1(%)-324.2(C)-1.6(I,)-319.7(0.21)5.1(0.94\),)-319.7(whi)5(c)-1.8(h)-323.2(r)-.6(eached)-323.2(statis-)]TJ
0 -1.1174 TD
-.0166 Tc
[(tical)-288.5(sig)5.3(n)-.4(icance.)-290.7(This)-288.2(asso)5.3(ciatio)5.3(n)-294.2(w)-1.3(as)-294(n)5.3(o)-.4(t)-288.5(s)-.2(tat)5.2(i)-.5(sti)5.2(cal)5.2(ly)-288.4(sign)5.3(i-)]TJ
0 -1.1116 TD
[(cant)-513.3(at)-513.3(hi)5.1(gher)-507.3(c)-1.7(yclin)5.2(g)-513.1(v)-.5(o)5.2(l)-.6(umes.)-509.7(A)-1.4(l)5.1(t)-.6(hou)5.2(gh)-513.1(i)5.1(t)-513.3(is)-507.2(dif)5.4(cul)5.1(t)-513.3(to)]TJ
T*
[(int)5.3(e)-1.5(rp)5.4(ret)-403.6(t)-.4(h)5.4(e)-404.7(imp)5.4(ort)5.3(ance)-410.4(o)5.4(f)-403.5(the)-404.7(o)-.3(b)5.4(s)-.1(erv)5.4(e)-1.5(d)-403.5(p)-.3(r)5.5(o)-.3(tectiv)5.4(e)-404.7(e)-1.5(ffect)-403.6(of)]TJ
0 -1.1174 TD
-.016 Tc
[(cy)5.9(clin)5.9(g)-305.1(3).2(.755)5.9(.7)5.9(5)-305.1(hour)6(s/week)-305.1(ob)5.9(serv)5.9(ed)-305.1(in)-305.1(the)-306.2(c)4.8(oho)5.9(rt,)-307.4(t)5.8(he)-306.2(low)]TJ
0 -1.1116 TD
-.0165 Tc
[(preval)5.3(e)-1.5(nce)-393.1(o)5.4(f)-391.9(i)5.3(nfertil)5.3(ity)-386.2(an)5.4(d)-392(a)4.3(bsence)-387.4(of)-386.2(di)5.3(rect)-386.3(relat)5.3(i)-.4(on)5.4(ship)-386.2(is)]TJ
T*
[(impor)5.4(tant)5.2(.)-348.3(T)4.2(he)-347.2(absence)-347.2(o)5.3(f)-346(a)-347.2(po)5.3(sit)5.2(i)-.5(ve)-347.2(associat)5.2(ion)-346(b)5.3(etween)-340.2(cy-)]TJ
0 -1.1174 TD
-.0163 Tc
[(cl)5.5(ing)-311.1(a)4.5(nd)-311.1(i)5.5(nfertil)5.5(ity)-305.4(all)5.5(a)-1.3(ys)-310.9(concern)5.6(s)-310.9(rai)5.5(s).1(ed)-305.4(by)-311.1(p)5.6(r)-.1(evi)5.5(ous)-305.2(stud)5.6(ies)]TJ
0 -1.1116 TD
-.017 Tc
[(ab)4.9(out)-214.1(observed)-219.7(a)-2(l)4.8(t)-.9(eratio)4.9(ns)-219.5(i)4.8(n)-219.7(sper)]TJ
12.8153 0 TD
[(m)-215.2(c)-2.1(haracteri)4.7(s)-.7(tics)-219.6(i)-1(n)-214(c)-2.1(yclis)5(ts.)]TJ
7.3823 0 0 6.5614 293.896 236.3527 Tm
-.0239 Tc
(11)Tj
9.843 0 0 9.843 62.022 221.0456 Tm
-.0165 Tc
[(It)-305.7(woul)5.3(d)-305.6(h)-.3(ave)-306.7(b)5.4(een)-299.8(of)-305.5(in)5.4(ter)5.5(e)-1.5(st)-305.7(t)5.3(o)-305.6(determin)5.4(e)-306.7(t)-.4(he)-301(sperm)-306.8(c)4.3(har)5.5(ac-)]TJ
0 -1.1174 TD
-.0169 Tc
[(terist)4.9(ics)-421(o)5(f)-421.1(t)-.8(h)5(e)-422.3(men)-421.2(b)-.7(efore)-416.6(ini)]TJ
12.176 0 TD
-.0165 Tc
[(tiation)-415(o)-.3(f)-420.7(h)5.4(abi)5.3(t)-.4(ual)-415.1(c)-1.5(yclin)5.4(g,)-417.3(al-)]TJ
-12.176 -1.1116 TD
-.0159 Tc
[(tho)6(ugh)-316.5(th)6(ese)-317.7(d).3(at)5.9(a)-323.4(w)5.2(ere)-317.7(n).3(o)6(t)-322.4(c)4.9(o).3(lle)4.9(cte)4.9(d).3(.)-318.8(N)-.6(e)4.9(v).3(er)6.1(the)4.9(l).2(ess)6.2(,)-318.8(thi)5.9(s)-322.1(st)5.9(udy)]TJ
T*
-.0158 Tc
[(de)5(mon)6.1(s).6(tra)5(t).3(es)-362.3(t)6(h).4(at)-356.9(conc)5(ern)6.1(s)-362.3(reg)6.1(a)-.8(rd)6.1(ing)-362.5(m)4.9(ale)-357.9(i).3(nf)6.2(erti)6(lit)6(y)-362.5(a)-.8(nd)-356.7(cy-)]TJ
T*
-.0165 Tc
[(cl)5.3(ing)-236.5(h)-.3(ave)-237.6(n)-.3(o)5.4(t)-242.4(b)5.4(een)-236.5(b)5.4(orn)-236.5(ou)5.4(t)-242.4(i)5.3(n)-236.5(a)-237.6(larg)5.4(e)-237.6(c)-1.5(ro)5.4(ss-secti)5.3(onal)-236.6(a)-1.5(nalysi)5.3(s.)]TJ
1.0137 -1.1174 TD
0 Tc
[(The)-310.9(ndings)-312.8(of)-313.2(this)-315.5(study)-310.7(demonstrated)-317.5(a)-313.3(direct)-314.4(relation-)]TJ
-1.0137 -1.1116 TD
[(ship)-326.9(between)-334.7(risk)-326.8(of)-330.5(prostate)-328(cancer)-333.8(and)-327(cycling)-327.1(volume)-331.7(in)]TJ
T*
[(cyclists)-235.8(aged)-237.1(over)-235.9(50)-232.6(years.)-235.7(This)-230.2(association)-240.2(was)-235.5(statistically)]TJ
0 -1.1174 TD
[(signicant)-387.8(after)-388(controlling)-388.1(for)-389.1(key)-384.6(confounding)-387.8(variables,)]TJ
0 -1.1116 TD
[(including)-264.9(age.)-268.2(In)-261.3(addition,)-267.2(there)-267.1(was)-270.1(no)-261.4(association)-269(between)]TJ
T*
[(cycling)-442.3(volume)-441.1(and)-436.4(primary)-442.1(care)-445.6(contact,)-441.1(suggesting)-438.3(that)]TJ
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